Radhika R

Prevalence Clinical Pathology and Treatment of Microfilariasis in Dogs in Thrissur - Mannuthy Department of Parasitology, College of Veterinary and Animal Sciences 1997



In a detailed study conducted on prevalence, clinical
pathology and treatment of microfilariasis in dogs in
Thrissur, it has been found that canine microfilariasis is
prevalent throughout the year with more incidence during
\
summer. The most reliable and accurate diagnostic method for
detecting microfilariae, was noted to be the Modified Knott's
Technique while wet film examination was more useful for



preliminary


screening.


Microfilariae


encountered


were



identified as those of


Dirofilaria repens.



The affected dogs revealed haematological changes like
increase in ESR, TLC, eosinophils as well as lymphocytes and



decrease in Hb, TEC, PCV as also neutrophils.


Biochemical



studies revealed increase in Serum Total Protein, Globulin,
AST, ALT, BUN as well as Serum Urea in microfilaraemic dogs
and higher levels of Albumin, Albumin/Globulin ratio in
non-microfilaraemic dogs.
Single oral dose of Milbemycin oxime at 0.5 mg/kg b.w.
was found to be the most effective drug for microfilariasis,
followed by single s/c dose of Ivermectin at 200 mg/kg b.w.
and 7 consecutive daily s/c dose of levamisole at 7.5 mg/kg.


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