Efficacy of Intrauterine Administration of Gentamicin in the Treatment of Clinical Endometritis in Crossbred Cattle (Record no. 25087)

000 -LEADER
fixed length control field 03589nam a2200169Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 636.082
Item number VAR/EF
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Varadarajan M
245 ## - TITLE STATEMENT
Title Efficacy of Intrauterine Administration of Gentamicin in the Treatment of Clinical Endometritis in Crossbred Cattle
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc Mannuthy
Name of publisher, distributor, etc Department of Animal Reproduction, College of Veterinary and Animal Sciences
Date of publication, distribution, etc 1985
300 ## - PHYSICAL DESCRIPTION
Extent .
502 ## - DISSERTATION NOTE
Dissertation note MVSc
520 3# - SUMMARY, ETC.
Abstract The objective of the study was to assess the efficacy of intrauterine infusion of Gentamicin, a bread spectrum antibiotic with deep tissue penetrance either alone or in combination with Stillboestrol in the treatment of clinical endometritis. Isolation of the infective organisms and sensitivity test were also carried out on a limited number of cases.
One hundred and seventy crossbred cows and heifer with clinical endomtritis formed the materials for the study. These animals were randomly allotted into two treatment groups. Group 1 comprising of 86 animals were given 250 mg of Gentamicin intrauterine and group 11 comprising 250 mg of Gentamicin intrauterine and group 11 comprising of 84 animals were given a combination of Gentamicin and 10 mg of Stilboestrol. Those animals which were completely free of infection were inseminated in the next heat and rest were given a second infusion of the above drugs. Conception rate was worked out both on 90 days non return rate and actual pregnancy verification. Uterine discharges from 25 animals were collected for bacterial isolation and sensitivity test.
Among 8352 cattle examined during the period of study 807 (9.66%) were found to be affected with clinical endometritis. Eighty six cases treated with Gentamicin gave a single insemination conception rate of 56.45 per cent with an overall conception rate of 72.58 per cent needing 1.91 inseminations per conception. On the ether hand, 84 cases receiving Gentamicin, Stilboestrol combination recorded a single insemination conception percentage of 40.90 with an overall conception of 63.63 per cent requiring 2.39 insemination per conception. There was no variation between groups with respect to percentage conception and average number of days from treatment to conception.
The percentage clinical recovery with single infusion in group 1 and 11 were found to be 96.51 and 94.03. The number of intrauterine infusion was not found to influence the conception rate and the recovery period. The study also revealed that the parity of the animal in both the treatment groups did not influence the effectiveness of the treatment with respect to percentage conception and the average number of days from treatment to conception.
It can be concluded that Gentamicin or Gentamicin Stillboestrol combination is equally effective in the treatment of clinical endomtritis. However, addition of Stillboestrol in the Gentamicin infusion did not have any added beneficial effect.
The bacterial isolates were Haemophilus (8%), Staphylococcus (20%), Bacillus (4%),Pasteurella (8%) Actinobacillus (4%), Heromonas (12%), Lectobacillus (4%)and Streptobacillus (4%). The sensitivity of the isolates to Gentamicin, Septran, Chloramphenicol, Tetracycline and Ampicillin were respectively 60, 44, 28, 28 and 8 per cent. Isolation and sensitivity study has proved that most of the isolates were sensitive to Gentamicin and hence it is considered to be a very effective antibiotic for treating uterine infection.
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name PrabhakaranNair P K (Guide)
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://krishikosh.egranth.ac.in/handle/1/5810094361
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Item type Theses
Holdings
Not for loan Permanent location Current location Shelving location Date acquired Full call number Barcode Date last seen Koha item type
  KAU Central Library, Thrissur KAU Central Library, Thrissur Theses 2014-03-18 636.082 VAR/EF 170131 2014-03-18 Theses
  KAU Central Library, Thrissur KAU Central Library, Thrissur Theses 2014-03-18 636.082 VAR/EF 171526 2014-03-18 Theses
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