Assessment of Immunity to Duck Plague Virus (Duck Virus Enteritis) on Vaccination (Record no. 25484)
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| 000 -LEADER | |
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| fixed length control field | 03580nam a2200193Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220211162219.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 140128s9999 xx 000 0 und d |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 636.089 6 |
| Item number | DIW/AS |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Diwakar Dattatrayrao Kulkarni |
| 245 ## - TITLE STATEMENT | |
| Title | Assessment of Immunity to Duck Plague Virus (Duck Virus Enteritis) on Vaccination |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc. | Mannuthy |
| Name of publisher, distributor, etc. | Department of Microbiology, College of Veterinary and Animal Sciences |
| Date of publication, distribution, etc. | 1993 |
| 502 ## - DISSERTATION NOTE | |
| Degree type | PhD |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | During 1991, six outbreaks, clinically suspected to be duck plague (DP) with 33 per cent morbidity and 26 per cent mortality were investigated. Duck plague virus was isolated from each outbreak. The isolates were able to produce the lesions and death of the duck embryos but failed to kill the chicken embryos during initial passages. One of the strains named DP – S was partially attenuated by 10 passages in chicken embryos following 20 passage in duck embryos. Though the attenuated strain did kill ducks, its pathogenicity index was reduced from 1.9 to 1.23. The isolate DP – S under transmission electron microscope revealed virions of herpes virus morphology. Two DP vaccines – commercial vaccine and lab – adapted vaccine having virus titres 0.74 and 3.5 log 10 ELD 50/ml respectively, were separately inoculated into four group of ducklings respectively, two groups receiving single dose and two receiving double dose of corresponding vaccines at an interval of four weeks. Another group of ducklings was kept as control without vaccination. Three ducks in each group were challenged with virulent DPV at four, eight and 20 weeks post – vaccination. The birds in all the five groups were screened at regular intervals for studying the immune response by virus neutralization (VN), leucocyte migration – inhibition (LMI) and passive haemagglutination (PHA) test. The challenged and survived birds were screened for the carrier status of DPV by examination of their rectal swabs for virus isolation. In an organized farm, 180 ducks were given commercial vaccine at one year of age and were screened for VN antibodies, LMI response and PHA titres before and eight weeks post – vaccination. Randomly selected two birds were challenged six weeks post – vaccination. The findings of the study are briefly listed as under: * Six duck plague outbreaks were investigated, the virus isolated, and characterized. It was partially attenuated in duck and chicken embryos. * The commercial vaccine could elicit very poor immune response as compared to laboratory adapted vaccine. The immunity could not last long even upto eight weeks in single vaccination and 20 weeks in double vaccination. * Single vaccination is not effective as compared to double vaccination given four weeks apart. * The assessment of antibody – mediated (AMI) and cell – mediated (CMI) immune responses indicated that both AMI and CMI are involved in protection of ducks against duck plague. * The vaccinated or vaccinated and infected birds did not show carrier status as attempts to isolate the virus from rectal swabs collected after vaccination and challenge were unsuccessful. * The PHA has been standardized for diagnosis of duck plague. |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | James P C (Guide) |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | https://krishikosh.egranth.ac.in/handle/1/5810143693 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | https://krishikosh.egranth.ac.in/displaybitstream?handle=1/5810143693&fileid=29311a94-4d9f-4528-a258-5f11a7e33858 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | |
| Koha item type | Theses |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Permanent Location | Current Location | Shelving location | Date acquired | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
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| KAU Central Library, Thrissur | KAU Central Library, Thrissur | Theses | 2014-03-18 | 636.089 6 DIW/AS | 170529 | 2014-03-18 | 2014-03-18 | Theses |