Evaluation of liver function in ruminal acidosis in goats (Record no. 25525)

000 -LEADER
fixed length control field 04462nam a2200193Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220223161433.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 140128s9999 xx 000 0 und d
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 636.089 6
Item number USH/EV
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Usha Narayana Pillai
245 ## - TITLE STATEMENT
Title Evaluation of liver function in ruminal acidosis in goats
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc. Mannuthy
Name of publisher, distributor, etc. Department of Clinical Medicine, College of Veterinary and Animal Sciences
Date of publication, distribution, etc. 1988
502 ## - DISSERTATION NOTE
Degree type MVSc
520 3# - SUMMARY, ETC.
Summary, etc. The results and conclusions drawn from a study on ruminal acidosis carried out to determine the incidence of disease in the field and clinical signs, changes in rumen liquor, blood and urine during the course of induced disease are presented, Based on the results effect of ruminal acidosis on the functional status of the liver was assessed to strengthen the diagnostic – therapeutic approaches hither – to adopted.
The available data on the incidence of disease collected from field Veterinary hospitals were utilized for analysis of digestive disorders in goats. Twenty apparently healthy cross – bred goats of either sex weighing 15.0 to 25.0 kg and of 1 – 3 years in age maintained under identical conditions of feeding and management at the University Livestock Farm (AICRP on Goats for Milk Production), Mannuthy were selected at random and utilized for the present study. They were divided into two groups of eight (Group – 1) and twelve (Group – 11) and fistulated by suitable surgical techniques. Animals of Group – 1 were used as healthy control for this study. Ruminal acidosis was induced in Group – 11 animals by intraruminal administration of crushed raw rice at @ 80 g/kg body weight. Course of the disease was followed and clinical observations were made daily. Rumen liquor, blood and urine samples were collected at 0, 24, 48, 72 and 96 hours of the experiment and analysed. Similarly samples were collected at 24 hourly intervals from animals of group – 1 and analysed to obtain the normal values.
Digestive disorders constituted 57.69 per cent of all diseases in goats. The incidence of primary digestive disorders was 29.37 per cent with acid indigestion forming 18.07 per cent. Seasonal variations in the incidence of ruminal acidosis were significant , the highest incidence was recorded during summer followed by rainy and winter seasons.
General depression, dullness, mild tympany, absence of reticulo – ruminal contractions, firm and doughy rumen on palpation, foul smelling diarrhoea, purulent nasal discharge, increased rates of pulse and respiration and signs of dehydration were the important clinical signs noticed in the study.
Rumen liquor samples collected from Group – 11 animals at 24 hours after induction of the disease were creamy, faintly sour to distinctly sour odour and watery in consistency. These physical characters of rumen liquor persisted during the rest of the period of observations. Complete absence of protozoal motility and SAT could be observed by 24 hours after induction of the disease. Significant decrease in the pH and NH3 – N with associated increase in lactic acid level were observed in all the samples of rumen liquor while decrease in the TVFA level was significant from the 48th hour of experiment. Significant increase in the blood glucose, lactic acid, GOT, LDH, GDH and T ½ of BSP with associated decrease in A:G ratio, cholesterol and fractional clearance of BSP from plasma were observed in animals in which ruminal acidosis was induced. However, total protein, albumin, GPT and NH3 – N levels in blood did not show any significant variations. Changes in the A:G ratio, GOT, LDH, GDH levels in the blood and fractional clearance of dye from the plasma indicated hepatic insufficiency. Urine samples did not reveal presence of any pathological constituents but a linear relationship was maintained between the pH of urine and rumen liquor.
Postmortem findings included peeling of rumen mucosae, congestion all along the gastro – intestinal tract, cardiac dilatation, petechial haemorrhage on myocardium, degeneration and necrosis of liver, distension of gallbladder with greenish – yellow tinged fluid and degeneration of kidney.
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Alikutty K M (Guide)
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier https://krishikosh.egranth.ac.in/handle/1/5810104366
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier https://krishikosh.egranth.ac.in/displaybitstream?handle=1/5810104366&fileid=c95be804-77b9-4d93-ba47-2f02e39d0c84
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Theses
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Shelving location Date acquired Full call number Barcode Date last seen Price effective from Koha item type
          KAU Central Library, Thrissur KAU Central Library, Thrissur Theses 2014-03-18 636.089 6 USH/EV 170570 2014-03-18 2014-03-18 Theses
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