Comparative study of Ketamine Hydrochloride and Thiopentone Sodium anaesthesia in birds (Record no. 26474)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 06801nam a2200169Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 636.089 7 |
| Item number | DEV/CO |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Devanand,C B |
| 245 ## - TITLE STATEMENT | |
| Title | Comparative study of Ketamine Hydrochloride and Thiopentone Sodium anaesthesia in birds |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc | Mannuthy |
| Name of publisher, distributor, etc | Department of Surgery, College of Veterinary and Animal Sciences |
| Date of publication, distribution, etc | 1991 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 113p. |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | MVSc |
| 520 3# - SUMMARY, ETC. | |
| Abstract | The present study was undertaken to assess the efficacy of (i) ketamine hydrochloride, (ii) thiopentone sodium, and (iii) ketamine hydrochloride followed by thiopentone sodium, for anaesthetising domestic chicken and ducks. Th~rty apparently healthy White Leghorn cocks, aged 18 - 20 weeks and weighing 1.120 - 1.920 kg (Group I) and thirty apparently heal thy White Pekin .dz-ake s , aged 20 - 22 weeks and weighing 1.700 - 2.100 kg (Group II) were used. Group I and II were further divided into three sub-groups, viz.,A, Band C consisting of ten birds each. Ketamine hydrochloride at the rate of 100 mg per kg bodyweight was administered in sub-group A, thiopentone sodium (2.5 per cent solution) at the rate of 15 mg per kg in sub-group B, and ketamine hydrochloride at the rate of 50 mg per kg followed by thiopentone sodium (2.5 per cent solution) at the rate of 7.5 mg per kg in sub-group C, in both the trials. The drugs were administered intraperi- toneally. During the onset of anaesthesia, when ketamine hydrochloride was administered, loss of balance, unsteadiness of head, cyanosis of comb and wattles, defaecation and vocalisation were noticed in chicken, but in ducks defaecation was not present. Ruffled feathers, dropping of wings, fluttering and wagging of tail were noticed as additional symptoms in ducks. When thiopentone sodium was administered, loss of balance, unsteadiness of head, cyanosis of comb and wattles, ruffled feathers and dropping of' wings were noticed in chicken, but in ducks vocalisation and fluttering were noticed in addition. When ketamine hydrochloride followed by thiopentone sodium was administered, loss of balance, unsteadiness of head, cyanosis of comb and wattles, dropping of neck and wings, and closing of eyelids were noticed in chicken and ducks. In ducks the onset was very quick. All the birds assumed sternal recumbency followed by lateral recumbency after the onset of anaesthesia. 2 As the effect of anaesthesia deepened, pedal reflexes were abolished in both the groups. However, other reflexes such as corneal, pupillary, palpebral and reflexes of the third eyelid, comb and wattles were persisting in chicken and ducks. During ketamine hydrochloride anaesthesia eyes were kept open, and when thiopentone sodium or ketamine hydrochloride followed by thiopentone sodium were administered, eyes were kept closed. In ducks, abolished when the reflexes of the third eyelid were ketamine hydrochloride followed by 3 thiopentone sodium was administered. The induction was smooth and uneventful in chicken and ducks. The time for induction was 7.30+0.53 min.,. 9.30+0.38 min. and 8.00+0.58 min. in sub-groups A, Band C respectively in chicken, and 9.20±.0.58 min., 10.20+0.87 min. and 4.60+0.70 min. in sub-groups A, Band C respecti vely in ducks. The time for induction was the least in chicken when ketamine hydrochloride was used, and ln ducks when ketamine hydrochloride followed by thiopentone sodium was used. The duration of anaesthesia was 63.40+2.16 min., 31.40+1.82 min. and 40.20+3.99 min. in sub-groups A, Band C respectively in chicken, and 35.90±2.43 min., 18.90+0.99 min. and 20.20+0.89 min. in sub-groups A, Band C respectively in .du ck s , The duration of anaesthesia was maximum when ketamine hydrochloride was administered and minimum when thiopentone sodium was administered in both the groups. 4 The duration of recovery was 135.50+9.24 min. in sub-group A, 149.60+8.32 mln. in sub~group B and 131.20+5.10 min. in . sub-group C, in chicken, and 84.50+7.31 min. in sub-group A, . 64.40+8.33 min. in sub-group Band 113.10+6.15 min. in sub-group C, in ducks. The duration of recovery was the least when ketamine hydrochloride followed by thiopentone sodium was used in chicken, and when thiopentone sodium was used in ducks. The recovery from anaesthesia was smooth and uneventful in both the groups. Vigorous shaking of the head was seen when ketamine hydrochloride was administered in ducks. There was reduction in cloacal temperature during anaesthesia. Respiration rate showed an initial rise followed by gradual reduction. The total erythrocyte count was decreased during anaesthesia. The total leukocyte count was decreased in sub-groups A and B, and increased in sub-group C, in chicken. There was an increase in total leukocyte count in ducks. Lymphocyte count was decreased, but heterophil count and eosinophil count were increased. There was no response to pain on incising and suturing the skin, muscles and peritoneum except for slight movement while incising the skin during ketamine hydrochloride anaesthesia. Focal congestion of liver and kidney were noticed on the 5th day. Mild degree of inflammatory reaction on the parietal peritoneum was noticed at the point of entry of the needle wherein thiopentone sodium was administered. From the results of present study, it could be found that intraperitoneal administration of ketamine hydrochloride, thiopentone sodium, and ketamine hydrochloride followed by thiopentone sodium resulted in satisfactory surgical plane of anaesthesia in chicken and ducks. For chicken, ketamine hydrochloride is preferred because of the comparatively least time for induction, prolonged duration of anaesthesia and recovery. Post anaesthetic complications were not found. In ducks the duration of anaesthesia was more, when ketamine hydrochloride was administered, but vigorous shaking of the head was seen during the period ofr~v.ay. Hence, for ducks, ketamine hydrochloride followed by thiopentone sodium is preferred because of the comparatively least time for induction and satisfactory duration of anaesthesia and recovery. |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Abraham Varkey C (Guide) |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | http://krishikosh.egranth.ac.in/handle/1/5810037979 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | |
| Item type | Theses |
| Not for loan | Permanent location | Current location | Shelving location | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Collection code |
|---|---|---|---|---|---|---|---|---|---|
| KAU Central Library, Thrissur | KAU Central Library, Thrissur | Theses | 2014-03-18 | 636.089 7 DEV/CO | 171531 | 2014-03-18 | Theses | ||
| Not For Loan | KAU Central Library, Thrissur | KAU Central Library, Thrissur | Theses | 2019-08-03 | 636.089 7 DEV/CO | 170295 | 2019-08-03 | Theses | Reference Book |