Morphological And Phytochemical Investigations On St.John`s Wort (Hypericum Spp.), a Potential Source Of Ant-HIV Compounds (Record no. 27014)

000 -LEADER
fixed length control field 03478nam a2200181Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220901154050.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 140128s9999 xx 000 0 und d
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 633.8
Item number GAN/MO
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Ganapathy V
245 ## - TITLE STATEMENT
Title Morphological And Phytochemical Investigations On St.John`s Wort (Hypericum Spp.), a Potential Source Of Ant-HIV Compounds
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc. Vellanikkara
Name of publisher, distributor, etc. Department of Plantation Crops and Spices, College of Horticulture
Date of publication, distribution, etc. 2003
502 ## - DISSERTATION NOTE
Degree type MSc
520 3# - SUMMARY, ETC.
Summary, etc. Renowned laboratories throughout the world have been makuu; uucnse search hi
detect and isolate potential chemicals from plants for curing AIDS. llvpcrtcmn is :\11
important genera yielding hypericin,a potential anti -I-IIV chemical I lvpcricin ll:l~
. been reported from many exotic Hypericum species. Investigations on the presence \Ii'
hypericin in the indigenous flora (H mysorense and H jU/JOl1iClIl1I) arc i:ldiJl~' I kill"
the present study entitled "Morphological and Phytochemical IJl\CSII!':lllllll~ .'11
St.Johns Wort (Hypericum spp.), a potential source or anti-HI V compounds" \I;I~
constituted.
Two species of Hypericum were located in Kerala; H mysorcnsc .u the high
ranges of Idukki and Wayanad districts and H. japonicum in Wayanad district. The
natural habitat characters of H mysorense were studied at Vattavada in IduUI
Phytosociological parameters such as density, abundance and per cent frequency were
determined by quatrat studies. H mysorense was often present or seldom present
,
along with Pteridium aquilinum, Eucalyptus grandis, Lantana camara, Strobilanthus
spp, Andropogon lividis and Chrysopogon zeylanicus in the high altitucle regions of
Vattavada panchayat of Idukki district Chrysopogon zeylanicus is the dominant
species in the eco system. H. mysorense is a shrub with stiff branches while H
japonicum is a prostrate herb growing in marshy lands. Translucent glands were either
streaks or dots in H. mysorense while it was pellucid dots in H japonicum. Stem
anatomy of H mysorense revealed presence of "type B" secretory canals whereas it
was absent in H japonicum.
Histochemical tests indicated the presence of lignin in the leaf,stem and root
of H. mysorense and H. japonicum. Leaf, stem and root of H. japonicum had
phenolic compounds while there was no indication for the presence of these
compounds in the stem of H. mysorense. The primary metabolites like starch, total
sugars,protein and total free amino acids on leaf, stem and root were quantified.
Qualitative test for anthraquinone was negative in both the species. When tested





using TLC for the presence of hypericin ,no spots corresponding to In \ .iluc o !
standard hypericin were observed in H. mysorense and H. japonicum samples
Commercial extract of H. perforatum (Eleve®,) had 0.22 to 0 25 per cell!
hypericin. Even though the samples of the indigenous Hypericum sP/' (//.
mysorense and H. japonicum ) were negative for hypericin - the target anti-l ll V
compound, they were indicative for the presence of anthronoid derivati ves. These
anthronoid derivatives could be the precursors or intermediary compounds for the
hypericin synthesis in the plant metabolism. These compounds need further
analysis for identification and characterization for anti-HfV property.

700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Mini Raj N (Guide)
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier https://krishikosh.egranth.ac.in/handle/1/5810154986
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Theses
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Shelving location Date acquired Full call number Barcode Date last seen Price effective from Koha item type
          KAU Central Library, Thrissur KAU Central Library, Thrissur Theses 2014-03-18 633.8 GAN/MO 172073 2014-03-18 2014-03-18 Theses
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