Ecg and biochemical changes in induced rumen acidosis Ii Goats
By: Shihabudheen P K.
Contributor(s): Usha Narayana Pillai (Guide).
Material type:
BookPublisher: Mannuthy Department of Clinical Medicine, College of Veterinary and Animal Sciences 1998DDC classification: 636.089 5 Online resources: Click here to access online | Click here to access online Dissertation note: MVSc Abstract: An experiment was carried out with twelve adult goats of
either sex to study the clinical manifestations of ruminal
acidosis, changes in the rumen liquor, haematology, serum
biochemistry, changes in the urine, electrocardiogram
variations and postmortem lesions.
The goats were maintained under identical management and
feeding cond'itions at University Goat Farm, Mannuthy and were
selected at random. One group of six animals served as
healthy controls and the other group was subjected to rumen
fistulation by standard surgical procedures. Acidosis was
induced by intraruminal administration of crushed rice at the
rate of 80 g/kg. Clinical signs were recorded, samples of
rumen liquor, blood and urine were collected and
electrocardiogram was recorded at 0, 12, 24, 48, 72 and 96 h
of experiment.
Clinical signs noticed were anorexia, increased pulse
and respiratory rate, depression, cessation of ruminal
contractions, oliguria, diarrhoea, sunken eyes, thick nasal
discharge and grinding of teeth.
Rumen liquor was creamy coloured, watery with sour odour
and the pH was 4.16 ± 0.05 and without any protozoa. There
was no sedimentation activity and MBRT was prolonged.
initially increased and then reduced.
TVFA
There was nonsignificant
increase in haemoglobin,
haemotocrit and cell:fluid ratio with significant increase
in ESR,
leukocytosis with significant neutrophilia and
lymphopenia were also present.
A significant increase in the serum glucose, phosphorus,
magnesiu~,
sodium,
potassium
lactate,
pyruvate
and
lactate:pyruvate
ratio
were
observed after
induction.
Significant r educ t i.on in calcium level also noted.
Urine pH reduced and there was protein, RBC cast,
leukocytes, renal epithelial cells and tripple phosphate
crystals in the urine.
ECG showed increase in heart rate, reduction in 'P'
amplitude, P duration, QT interval and PR interval. 'T'
amplitude increased nonsignificantly with a significant
increase in 'T' duration. Sinus tachycardia, ST elevation and
ST depression were also observed.
Post mortem lesions included sloughing of rumen mucosa,
abomasal ulcers, severe enteritis, focal necrosis of liver,
cholestasis, congestion of lungs and kidney, dilatation of
heart and oedema of brain.
| Item type | Current location | Call number | Status | Date due | Barcode |
|---|---|---|---|---|---|
Theses
|
KAU Central Library, Thrissur Theses | 636.089 5 SHI/EC (Browse shelf) | Available | 171390 |
MVSc
An experiment was carried out with twelve adult goats of
either sex to study the clinical manifestations of ruminal
acidosis, changes in the rumen liquor, haematology, serum
biochemistry, changes in the urine, electrocardiogram
variations and postmortem lesions.
The goats were maintained under identical management and
feeding cond'itions at University Goat Farm, Mannuthy and were
selected at random. One group of six animals served as
healthy controls and the other group was subjected to rumen
fistulation by standard surgical procedures. Acidosis was
induced by intraruminal administration of crushed rice at the
rate of 80 g/kg. Clinical signs were recorded, samples of
rumen liquor, blood and urine were collected and
electrocardiogram was recorded at 0, 12, 24, 48, 72 and 96 h
of experiment.
Clinical signs noticed were anorexia, increased pulse
and respiratory rate, depression, cessation of ruminal
contractions, oliguria, diarrhoea, sunken eyes, thick nasal
discharge and grinding of teeth.
Rumen liquor was creamy coloured, watery with sour odour
and the pH was 4.16 ± 0.05 and without any protozoa. There
was no sedimentation activity and MBRT was prolonged.
initially increased and then reduced.
TVFA
There was nonsignificant
increase in haemoglobin,
haemotocrit and cell:fluid ratio with significant increase
in ESR,
leukocytosis with significant neutrophilia and
lymphopenia were also present.
A significant increase in the serum glucose, phosphorus,
magnesiu~,
sodium,
potassium
lactate,
pyruvate
and
lactate:pyruvate
ratio
were
observed after
induction.
Significant r educ t i.on in calcium level also noted.
Urine pH reduced and there was protein, RBC cast,
leukocytes, renal epithelial cells and tripple phosphate
crystals in the urine.
ECG showed increase in heart rate, reduction in 'P'
amplitude, P duration, QT interval and PR interval. 'T'
amplitude increased nonsignificantly with a significant
increase in 'T' duration. Sinus tachycardia, ST elevation and
ST depression were also observed.
Post mortem lesions included sloughing of rumen mucosa,
abomasal ulcers, severe enteritis, focal necrosis of liver,
cholestasis, congestion of lungs and kidney, dilatation of
heart and oedema of brain.
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