Hepato-renal pathology in canines
By: Lakshmi R.
Contributor(s): Koshy Varghese(Guide).
Material type:
BookPublisher: Mannuthy Department of Plantation crops spices, Veterinary College, 2001DDC classification: 636.089 6 Online resources: Click here to access online Dissertation note: MVSc Abstract: The present investigation was undertaken to assess
the prevalence and pathology of the liver and kidney
disorders in canines. The results of the present
investigation and the evaluation of data from the
records revealed a high incidence of liver (76 per
cent) and kidney (85 per cent) disorders. A detailed
systematic examination of one hundred cases of canine
carcasses brought for autopsy during the period of
investigation was
conducted and the
gross
and
histopathological lesions were studied in detail and
were classified based on age, sex and breed.
Vascular and degenerative changes were the
predominant lesions in these organs. The other lesions
recorded in the liver were necrosis (15 cases),
hepatitis (19 cases), fibrosis (9 cases) and cirrhosis
(2 cases). One case each of cholangiocarcinoma, hepatic
cyst and adhesion of diaphragm and the liver was
encountered in the present study. Among kidney
disorders, glomerular lesions were predominant next to
vascular and degenerative changes. A total of 59 cases
had some lesions in the glomeruli of wh i ch , 32 had
glomerulonephritis. PGN was the predominant type of
glomerulonephritis. Males had a higher predilection for
ii-
PGN and it was common in animals less than three years
of age. MN and MPGN were common in animals more than
three years of age.
lesions and their
The high incidence of glomerular
possible causes were discussed.
Tubulo-interstitial nephritis was observed in 16 cases.
Interstitial nephritis was common in males while both
cases of pyelonephritis were seen in females. Acute
interstitial nephritis was seen in animals less than
five years of age wh i.Le all cases of I chronic
interstitial nephritis was seen in animals more than
five years of age.
Bacterial isolations were obtained in the liver or
kidney or both in only 14 cases. Viral etiology was
suspected in tv « o cases \ ...• here intranuclear inclusions
were seen in the hepatocytes and the glomerular
epithelium. The high incidence of vascular lesions
without any evidence for infectious etiology in rest of
the animals suggested the involvement of some toxic
factors. The importance of identifying the specific
etiology in these suspected cases of toxic conditions
and the need and scope for further studies in these
lines were highlighted.
| Item type | Current location | Call number | Status | Date due | Barcode |
|---|---|---|---|---|---|
Theses
|
KAU Central Library, Thrissur Theses | 636.089 6 LAK/HE (Browse shelf) | Available | 171785 |
MVSc
The present investigation was undertaken to assess
the prevalence and pathology of the liver and kidney
disorders in canines. The results of the present
investigation and the evaluation of data from the
records revealed a high incidence of liver (76 per
cent) and kidney (85 per cent) disorders. A detailed
systematic examination of one hundred cases of canine
carcasses brought for autopsy during the period of
investigation was
conducted and the
gross
and
histopathological lesions were studied in detail and
were classified based on age, sex and breed.
Vascular and degenerative changes were the
predominant lesions in these organs. The other lesions
recorded in the liver were necrosis (15 cases),
hepatitis (19 cases), fibrosis (9 cases) and cirrhosis
(2 cases). One case each of cholangiocarcinoma, hepatic
cyst and adhesion of diaphragm and the liver was
encountered in the present study. Among kidney
disorders, glomerular lesions were predominant next to
vascular and degenerative changes. A total of 59 cases
had some lesions in the glomeruli of wh i ch , 32 had
glomerulonephritis. PGN was the predominant type of
glomerulonephritis. Males had a higher predilection for
ii-
PGN and it was common in animals less than three years
of age. MN and MPGN were common in animals more than
three years of age.
lesions and their
The high incidence of glomerular
possible causes were discussed.
Tubulo-interstitial nephritis was observed in 16 cases.
Interstitial nephritis was common in males while both
cases of pyelonephritis were seen in females. Acute
interstitial nephritis was seen in animals less than
five years of age wh i.Le all cases of I chronic
interstitial nephritis was seen in animals more than
five years of age.
Bacterial isolations were obtained in the liver or
kidney or both in only 14 cases. Viral etiology was
suspected in tv « o cases \ ...• here intranuclear inclusions
were seen in the hepatocytes and the glomerular
epithelium. The high incidence of vascular lesions
without any evidence for infectious etiology in rest of
the animals suggested the involvement of some toxic
factors. The importance of identifying the specific
etiology in these suspected cases of toxic conditions
and the need and scope for further studies in these
lines were highlighted.
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