Seroconversion of three different foot-and-mouth disease vaccines in cattle
By: Bipin K C.
Contributor(s): Tresamol PV (Guide).
Material type:
BookPublisher: Mannuthy Department of Veterinary Epidemology, College of Veterinary and Animal Sciences 2001DDC classification: 636.089 4 Online resources: Click here to access online Dissertation note: MVSc Abstract: Seroconversion of three different commercial inactivated quadrivalent
Foot-and-Mouth disease vaccines were studied. One aluminium hydroxide gel
vaccine and two oil-adjuvanted vaccines were used for the study in three groups
of cattle. Monthly assessment of antibody titres against 0, A, C and Asia-I
antigens were made by liquid phase blocking-ELlS A (LPB-ELISA).
Unvaccinated calves of four months and above age were grouped into three and
vaccinations were made as per manufacturer's regime.
Group I and group Il animals did not showed significant difference in
type ° antibody titres throughout the study period except following booster
vaccination of group I in seventh month. Both groups maintained protective
titres except in the fourth and fifth months of study. Group III showed a lower
level of antibody titres throughout the study period.
Protective typeA antibody titres were maintained by group I and group
H animals during the entire study period except in the fifth month. No
significant difference between these two groups observed except following the
second booster vaccination in group H. Group III showed comparatively lower
antibody titres against type A FMD antigen.
"
All the three groups showed protective mean type C antibody titres
throughout the study period. But group III showed an antibody titre below
protective level during fourth month. Group I and group II did not show
significant variation in antibody titres except following respective booster
vaccinations.
Group I and group II maintained a protective level of type Asia-l
antibody titres except during fifth month. Group III showed significantly low
Asia-l antibody titres throughout the study period.
The booster vaccinations produced anamnestic response in group I and
group Il in almost all cases. Group III animals showed lower antibody titres
against all the four virus types when compared to group I and group Il and
response to booster vaccinations were poor in group Ill.
Comparison between the three vaccines in terms of cost required for
immunising a single animal for the first one year revealed that oil-adjuvanted
vaccine Il required the lowest cost while oil-adjuvanted vaccine III required the
highest cost for the first one year.
| Item type | Current location | Call number | Status | Date due | Barcode |
|---|---|---|---|---|---|
Theses
|
KAU Central Library, Thrissur Theses | 636.089 4 BIP?SE (Browse shelf) | Available | 171906 |
MVSc
Seroconversion of three different commercial inactivated quadrivalent
Foot-and-Mouth disease vaccines were studied. One aluminium hydroxide gel
vaccine and two oil-adjuvanted vaccines were used for the study in three groups
of cattle. Monthly assessment of antibody titres against 0, A, C and Asia-I
antigens were made by liquid phase blocking-ELlS A (LPB-ELISA).
Unvaccinated calves of four months and above age were grouped into three and
vaccinations were made as per manufacturer's regime.
Group I and group Il animals did not showed significant difference in
type ° antibody titres throughout the study period except following booster
vaccination of group I in seventh month. Both groups maintained protective
titres except in the fourth and fifth months of study. Group III showed a lower
level of antibody titres throughout the study period.
Protective typeA antibody titres were maintained by group I and group
H animals during the entire study period except in the fifth month. No
significant difference between these two groups observed except following the
second booster vaccination in group H. Group III showed comparatively lower
antibody titres against type A FMD antigen.
"
All the three groups showed protective mean type C antibody titres
throughout the study period. But group III showed an antibody titre below
protective level during fourth month. Group I and group II did not show
significant variation in antibody titres except following respective booster
vaccinations.
Group I and group II maintained a protective level of type Asia-l
antibody titres except during fifth month. Group III showed significantly low
Asia-l antibody titres throughout the study period.
The booster vaccinations produced anamnestic response in group I and
group Il in almost all cases. Group III animals showed lower antibody titres
against all the four virus types when compared to group I and group Il and
response to booster vaccinations were poor in group Ill.
Comparison between the three vaccines in terms of cost required for
immunising a single animal for the first one year revealed that oil-adjuvanted
vaccine Il required the lowest cost while oil-adjuvanted vaccine III required the
highest cost for the first one year.
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