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Haematological And Biochemical Changes In Cattle Of Floor With Special Refference To Endosulfan

By: Jyotsana Menon.
Contributor(s): Gopakumar N (Guide).
Material type: materialTypeLabelBookPublisher: Mannuthy Department of Pharmacology and Toxicology, College of Veterinary and Animal Sciences 2002DDC classification: 636.089 5 Online resources: Click here to access online Dissertation note: MVSc Abstract: A study was undertaken to assess the impact of environmental pollution with endosulfan in cattle of Eloor industrial belt. Hindustan Insecticide Limited is the major industrial unit handling endosulfan is situated here. So this area was selected for the conduct of study. Field samples like sludge, water and fodder and biological samples like blood, dung, urine and milk of cattle in the study area were collected. The collected samples were analysed for endosulfan level by gas liquid chromatography and compared (statistically) with those of control samples collected from University Livestock Farm (ULF), Mannuthy. A higher level of endosulfan could be detected in the field and biological samples ofEloor cattle than control animals. Milk samples collected from both Eloor area and ULF, Mannuthy had no detectable level of endosulfan in them except for one sample from the study area. Fodder was suspected to be the main source of endosulfan to cattle. A significant change was noticed in lymphocyte count, neutrophil and eosinophil count of the animals in affected area. Other haematologic values like total leucocyte count, total erythrocyte count, packed cell volume and erythrocyte indices (MC V, MCH, MCHC) did not show any significant di fferences. Eventhough the biochemical parameters like the creatinine phosphokinase and BUN level showed significant difference between test and control animals, these were within the normal range. It can be inferred that the levels of endosulfan in the field and biological samples were not sufficient enough to cause toxic symptoms and the variations in haematological and biochemical parameters might be due to role of other contaminants apart from endosulfan. However it could be concluded that field and biological samples collected from vicinities of Hindustan insecticides Ltd. were contaminated with endosulfan. The higher than normal endosulfan level in all samples may be looked with caution because of its toxic nature.
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MVSc

A study was undertaken to assess the impact of environmental pollution
with endosulfan in cattle of Eloor industrial belt. Hindustan Insecticide Limited
is the major industrial unit handling endosulfan is situated here. So this area
was selected for the conduct of study.
Field samples like sludge, water and fodder and biological samples like
blood, dung, urine and milk of cattle in the study area were collected. The
collected samples were analysed for endosulfan level by gas liquid
chromatography and compared (statistically) with those of control samples
collected from University Livestock Farm (ULF), Mannuthy.
A higher level of endosulfan could be detected in the field and
biological samples ofEloor cattle than control animals. Milk samples collected
from both Eloor area and ULF, Mannuthy had no detectable level of endosulfan
in them except for one sample from the study area. Fodder was suspected to be
the main source of endosulfan to cattle.
A significant change was noticed in lymphocyte count, neutrophil and
eosinophil count of the animals in affected area. Other haematologic values
like total leucocyte count, total erythrocyte count, packed cell volume and
erythrocyte indices (MC V, MCH, MCHC) did not show any significant
di fferences. Eventhough the biochemical parameters like the creatinine

phosphokinase and BUN level showed significant difference between test and
control animals, these were within the normal range.
It can be inferred that the levels of endosulfan in the field and biological
samples were not sufficient enough to cause toxic symptoms and the variations
in haematological and biochemical parameters might be due to role of other
contaminants apart from endosulfan. However it could be concluded that field
and biological samples collected from vicinities of Hindustan insecticides Ltd.
were contaminated with endosulfan. The higher than normal endosulfan level
in all samples may be looked with caution because of its toxic nature.

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