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Assessment Of Dichlorodiphenyltrichloroethane (ddt ) Residues In Cattle Of Floor area

By: Deepa AK.
Contributor(s): Usha P T A (Guide).
Material type: materialTypeLabelBookPublisher: Mannuthy Department of Pharmacology and Toxicology, College of Veterinary and Animal Sciences 2003DDC classification: 636.089 5 Online resources: Click here to access online Dissertation note: MVSc Abstract: A study was conducted to assess the impact of environmental pollution with DDT in cattle of Eloor industrial belt. Hindustan Insecticides Limited (HIL) is the major pesticide manufacturing factory of the region producing pesticides like ODT. Hence Eloor was selected as the study area. Environmental samples like sludge, water and fodder, biological samples like blood, urine, dung and milk were collected from the cattle of Eloor area. Whole blood and serum samples were collected for haematology and serum biochemistry respectively. The collected samples were analysed for ODT residues in the gas liquid chromatograph (GLC). The values obtained were compared statistically with the samples collected from University Livestock Farm, Mannuthy. Higher levels of DOT residues were obtained from the environmental and biological samples from Eloor than the corresponding samples from Mannuthy. The mean levels of total 'nOT in environmental samples of Eloor were 1.463 ± 0.555 ppm (fodder), 0.00255 ± 0.00002 ppm (water) and 35.157 ± 0.198 ppm (sludge). Biological samples from Eloor contained mean total ODT of 0.201 ± 0.123 ppm (serum), 0.023 ± 0.006 (urine), 0.910 ± 0.689 ppm (dung) and 0.058 ± 0.019 ppm (milk). Environmental samples from Mannuthy contained mean total DDT of 0.062 ± 0.021 ppm, 0.011 ± 0.006 ppm, 0.000085 ± 0.00007 ppm in fodder, sludge and water respectively. Serum, urine and dung from cattle of Mannuthy contained mean total DOT of 0.252 ± 0.145 ppm, 0.030 ± 0.003 ppm and 0.026 ± 0.017 ppm respectively. No DOT residues were detected in the milk samples from Mannuthy. The haematological values from Eloor cattle remained within the normal range except differential leucocyte count which exhibited marked neutropenia and eosinophilia. Values of total protein and albumin were normal in both groups of animals. Serum enzymes like alanine aminotransferase and aspartate aminotransferase were significantly different fr~m Mannuthy sample but were within the normal range. It can be inferred that the DDT residues present in the field and biological samples were not high enough to cause toxicity in cattle. Variation in the haematological and biochemical parameters may be due to the presence of other environmental pollutants along with DDT in the discharged industrial effluents.
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636.089 5 DEE/As (Browse shelf) Available 172063

MVSc

A study was conducted to assess the impact of environmental pollution
with DDT in cattle of Eloor industrial belt. Hindustan Insecticides Limited
(HIL) is the major pesticide manufacturing factory of the region producing
pesticides like ODT. Hence Eloor was selected as the study area.
Environmental samples like sludge, water and fodder, biological
samples like blood, urine, dung and milk were collected from the cattle of Eloor
area. Whole blood and serum samples were collected for haematology and
serum biochemistry respectively. The collected samples were analysed for
ODT residues in the gas liquid chromatograph (GLC). The values obtained
were compared statistically with the samples collected from University
Livestock Farm, Mannuthy.
Higher levels of DOT residues were obtained from the environmental
and biological samples from Eloor than the corresponding samples from
Mannuthy. The mean levels of total 'nOT in environmental samples of Eloor
were 1.463 ± 0.555 ppm (fodder), 0.00255 ± 0.00002 ppm (water) and 35.157
± 0.198 ppm (sludge). Biological samples from Eloor contained mean total
ODT of 0.201 ± 0.123 ppm (serum), 0.023 ± 0.006 (urine), 0.910 ± 0.689 ppm
(dung) and 0.058 ± 0.019 ppm (milk). Environmental samples from Mannuthy
contained mean total DDT of 0.062 ± 0.021 ppm, 0.011 ± 0.006 ppm, 0.000085
± 0.00007 ppm in fodder, sludge and water respectively. Serum, urine and

dung from cattle of Mannuthy contained mean total DOT of 0.252 ± 0.145
ppm, 0.030 ± 0.003 ppm and 0.026 ± 0.017 ppm respectively. No DOT
residues were detected in the milk samples from Mannuthy.
The haematological values from Eloor cattle remained within the normal
range except differential leucocyte count which exhibited marked neutropenia
and eosinophilia. Values of total protein and albumin were normal in both
groups of animals. Serum enzymes like alanine aminotransferase and aspartate
aminotransferase were significantly different fr~m Mannuthy sample but were
within the normal range. It can be inferred that the DDT residues present in the
field and biological samples were not high enough to cause toxicity in cattle.
Variation in the haematological and biochemical parameters may be due to the
presence of other environmental pollutants along with DDT in the discharged
industrial effluents.

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