Clinico-therapeutic studies on bacterial infection of respiratory tract in bovines
By: Siji P C.
Contributor(s): Vijayakumar K (Guide).
Material type:
BookPublisher: Mannuthy Department of Veterinary Epidemiolog and Preventive Medicine, College of Veterinary and Animal Sciences 2003DDC classification: 636.089 4 Online resources: Click here to access online Dissertation note: MVSc Abstract: The present study was undertaken to know the bacterial etiology,
antibiogram and to evaluate efficacy of two antibiotics namely enrofloxacin
(Gyroflox) at 5 mglkg body weight intramuscular once daily for 3 to 5 days and
florfenicol (Nuflor®) at 20 mg/kg body weight, deep intramuscular two doses at
48 h interval in the treatment of bovine respiratory tract infection.
The animals in the experimental groups were categorized according to a
clinical illness index score system. Clinical data and haematological parameters
of diseased animals showed significant difference with regard to temperature,
respiratory rate, erythrocyte sedimentation rate, packed cell volume, haemoglobin
and total erythrocyte count. No significant difference was noted in the values of
erythrocyte indices and leukogram. Bacteria isolated from the respiratory tract of
diseased bovines were Staphylococcus aureus (6), Staphylococcus epidermidis
(5), Streptococcus pyogenes (8), Escherichia coli (7), Klebsiella pneumoniae (5),
Pseudomonas aeruginosa (4), Mannheimia haemolytica (3) and Proteus vulgaris
(1). Out of the 39 bacterial isolates 19 (48.71 per cent) were Gram positive and
20 (51.29 per cent) were Gram negative. Single bacteria could be isolated only
from 2 cases (11.11 per cent). Mixed bacteria were isolated from 16 cases (88.88
per cent). Antibiotic sensitivity pattern of the isolates showed maximum
sensitivity to enrofloxacin (94.87 per cent) followed by ciprofloxacin (87.18 per
cent), chloramphenicol (76.92 per cent), gentamicin (64.10 per cent),
oxytetracycline (53.85 per cent), amoxycillin (51.28 per cent), streptomycin
(35.90 per cent) and trimethoprim (28.21 per cent).
Recovery of the animals in both groups was assessed on the basis of
statistically significant reduction in pyrexia, respiratory rate and overall
improvement of clinical signs and illness index score. Recovered animals
recorded a significant difference in the ESR and pev from diseased animals in
both the groups. No significant difference was noted in the temperature,
respiratory rate, haematological parameters between the two post-treatment
groups. Efficacy of both enrofloxacin and florfenicol was comparable in
counteracting bacterial bovine respiratory tract infection.
| Item type | Current location | Call number | Status | Date due | Barcode |
|---|---|---|---|---|---|
Theses
|
KAU Central Library, Thrissur Theses | 636.089 4 SIJ/CL (Browse shelf) | Available | 172237 |
MVSc
The present study was undertaken to know the bacterial etiology,
antibiogram and to evaluate efficacy of two antibiotics namely enrofloxacin
(Gyroflox) at 5 mglkg body weight intramuscular once daily for 3 to 5 days and
florfenicol (Nuflor®) at 20 mg/kg body weight, deep intramuscular two doses at
48 h interval in the treatment of bovine respiratory tract infection.
The animals in the experimental groups were categorized according to a
clinical illness index score system. Clinical data and haematological parameters
of diseased animals showed significant difference with regard to temperature,
respiratory rate, erythrocyte sedimentation rate, packed cell volume, haemoglobin
and total erythrocyte count. No significant difference was noted in the values of
erythrocyte indices and leukogram. Bacteria isolated from the respiratory tract of
diseased bovines were Staphylococcus aureus (6), Staphylococcus epidermidis
(5), Streptococcus pyogenes (8), Escherichia coli (7), Klebsiella pneumoniae (5),
Pseudomonas aeruginosa (4), Mannheimia haemolytica (3) and Proteus vulgaris
(1). Out of the 39 bacterial isolates 19 (48.71 per cent) were Gram positive and
20 (51.29 per cent) were Gram negative. Single bacteria could be isolated only
from 2 cases (11.11 per cent). Mixed bacteria were isolated from 16 cases (88.88
per cent). Antibiotic sensitivity pattern of the isolates showed maximum
sensitivity to enrofloxacin (94.87 per cent) followed by ciprofloxacin (87.18 per
cent), chloramphenicol (76.92 per cent), gentamicin (64.10 per cent),
oxytetracycline (53.85 per cent), amoxycillin (51.28 per cent), streptomycin
(35.90 per cent) and trimethoprim (28.21 per cent).
Recovery of the animals in both groups was assessed on the basis of
statistically significant reduction in pyrexia, respiratory rate and overall
improvement of clinical signs and illness index score. Recovered animals
recorded a significant difference in the ESR and pev from diseased animals in
both the groups. No significant difference was noted in the temperature,
respiratory rate, haematological parameters between the two post-treatment
groups. Efficacy of both enrofloxacin and florfenicol was comparable in
counteracting bacterial bovine respiratory tract infection.
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