TY  - BOOK
AU  - Sindhu O K 
AU  - Baby P G (Guide)
TI  - Effect of trisodium citrate in the treatement of mastitis in cattle
U1  - 636.089 5 
PY  - 2003///
CY  - Mannuthy
PB  - Department of Clinical Medicine, College of Veterinary and Animal Sciences
N2  - A study was conducted in the Department of Clinical Medicine, College 
of Veterinary and Animal Sciences, Mannuthy, for a period of three semesters 
during the year 2002 and 2003, to assess the efficacy of oral administration oftri- 
sodium citrate as therapeutic agent in subclinical mastitis of cattle and as a 
supportive treatment along with antibiotic in clinical mastitis of cattle and to 
evaluate the levels of pH, citric acid, calcium, lactose and chloride in milk of 
cattle affected with mastitis. 
Twenty cases of subclinical mastitis and fifteen cases of clinical mastitis 
were utilized for the study. Subclinical mastitis cases were divided in to three 
groups and clinical mastitis cases divided into two groups based on the 
therapeutic trial adopted. 
Gram positive cocci were isolated from cases in which the milk appeared 
white, cream, slight yellow or yellow coloured with fine clots or flakes. Gram 
negative coccobacilli were isolated from cases in which the milk appeared straw 
or yellow coloured watery milk with clots or without clots. Gram positive cocci 
were isolated from majority of the subclinical and clinical mastitis cases than the 
gram negative coccobacilli. 
Gram positive cocci were, highly sensitive to enrofloxacin, cephotaxime 
and ciprofloxacin. Gram negative coccobacilli were highly sensitive to 
chloramphenicol, trimethoprim, gentamicin, Enrofloxacin, Cefotaxime and 
ciprofloxacin. 
The pH and chloride levels of the affected quarter milk in subclinical and 
clinical mastitis cases before the treatment showed significant increase compared 
to the nonaffected quarter milk values. These values showed significant decrease 
to normal level on post treatment. 
 
The mean values of citric acid, lactose and calcium levels of the affected 
quarter milk in subclinical and clinical mastitis cases before the treatment, 
showed significant decrease before treatment when compared to the nonaffected 
quarter milk values. These values significantly increased and reached normal 
levels after treatment. 
Oral administration of tri-sodium citrate was found to be effective in 
treating subclinical mastitis cases. All the biochemical parameters of milk came 
to normal level in all cases in the trisodium citrate alone treated group by sixth 
day of treatment and also the increase in milk production after the treatment was 
slightly better in this group. 
Oral administration of tri-sodium citrate along with antibiotic was found 
to be effective in managing clinical mastitis cases. 100 percent bacteriological 
cure was observed in this group whereas only 75per cent bacteriological cure 
observed in the other group. 


UR  - https://krishikosh.egranth.ac.in/handle/1/5810106324
ER  -