TY  - BOOK
AU  - Siji P C 
AU  - Vijayakumar K (Guide)
TI  - Clinico-therapeutic studies on bacterial infection of respiratory tract in bovines
U1  - 636.089 4 
PY  - 2003///
CY  - Mannuthy
PB  - Department of Veterinary Epidemiolog and Preventive Medicine, College of Veterinary  and Animal Sciences
N2  - The present study was undertaken to know the bacterial etiology, 
antibiogram and to evaluate efficacy of two antibiotics namely enrofloxacin 
(Gyroflox) at 5 mglkg body weight intramuscular once daily for 3 to 5 days and 
florfenicol (Nuflor®) at 20 mg/kg body weight, deep intramuscular two doses at 
48 h interval in the treatment of bovine respiratory tract infection. 
The animals in the experimental groups were categorized according to a 
clinical illness index score system. Clinical data and haematological parameters 
of diseased animals showed significant difference with regard to temperature, 
respiratory rate, erythrocyte sedimentation rate, packed cell volume, haemoglobin 
and total erythrocyte count. No significant difference was noted in the values of 
erythrocyte indices and leukogram. Bacteria isolated from the respiratory tract of 
diseased bovines were Staphylococcus aureus (6), Staphylococcus epidermidis 
(5), Streptococcus pyogenes (8), Escherichia coli (7), Klebsiella pneumoniae (5), 
Pseudomonas aeruginosa (4), Mannheimia haemolytica (3) and Proteus vulgaris 
(1). Out of the 39 bacterial isolates 19 (48.71 per cent) were Gram positive and 
20 (51.29 per cent) were Gram negative. Single bacteria could be isolated only 
from 2 cases (11.11 per cent). Mixed bacteria were isolated from 16 cases (88.88 
per cent). Antibiotic sensitivity pattern of the isolates showed maximum 
sensitivity to enrofloxacin (94.87 per cent) followed by ciprofloxacin (87.18 per 
cent), chloramphenicol (76.92 per cent), gentamicin (64.10 per cent), 
oxytetracycline (53.85 per cent), amoxycillin (51.28 per cent), streptomycin 
(35.90 per cent) and trimethoprim (28.21 per cent). 
Recovery of the animals in both groups was assessed on the basis of 
statistically significant reduction in pyrexia, respiratory rate and overall 
improvement of clinical signs and illness index score. Recovered animals 
 
recorded a significant difference in the ESR and pev from diseased animals in 
both the groups. No significant difference was noted in the temperature, 
respiratory rate, haematological parameters between the two post-treatment 
groups. Efficacy of both enrofloxacin and florfenicol was comparable in 
counteracting bacterial bovine respiratory tract infection. 


UR  - https://krishikosh.egranth.ac.in/handle/1/5810106502
ER  -