TY  - BOOK
AU  - Madhanmohan M 
AU  - Tresamol P V (Guide)
TI  - Comparative seroconversion of Foot-And-Mouth disease vaccines in goats
U1  - 636.0894 
PY  - 2003///
CY  - Mannuthy
PB  - Department of Veterinary Epidemiology and Preventive Medicine, College of Veterinary and Animal Sciences
N2  - The comparative seroconversions of two different foot-and-mouth disease 
vaccines in goats were studied. Group I animals were vaccinated with inactivated 
quadrivalent aluminium hydroxide gel saponin adjuvanted FMD vaccine. Group 
11 animals were vaccinated with inactivated quadrivalent FMD oil-adjuvant 
vaccine as per the manufacture's schedule. Vaccinations were done in 
unvaccinated goats above four month of age. The antibody titre against foot and 
mouth disease virus types 0, A, C and Asia-I were assessed by liquid phase 
blocking ELISA. 
Group I animals showed the protective titre of type ° antibody titres 
throughout the period except sixth, tenth, eleventh and twelfth month. Group 11 
animals showed the protective level throughout the study period except seventh, 
eighth and ninth month. 
Both the groups showed the protective titre of type A, C and Asia-I 
antibody titres throughout the study period up to 12 months. All the vaccination 
including primary and booster vaccinations produce increase in antibody titre. 
Both the groups did not show any significant variation in antibody titres 
against FMDV type 0, A, C and Asia-I except the time of booster vaccination. 
Kids born from both the ~roups showed the protective level of type ° 
maternal antibody only upto one week of age where as protective level for type A 
and C maternal antibodies upto four weeks of age. 
Group I kids maintained the protective level of type Asia-I upto two 
weeks of age where as Group 11 maintained upto three weeks of age. 
 
From this observation it is concluded that 
1.	Both the group of vaccine provides sufficient protective titre for FMDV 
type 0, A, C and Asia-l . 
2.	Aluminium hydroxide gel vaccine performance is equally good as that of 
oil adjuvanted vaccine. 
3.	Oil-adjuvanted vaccine reduces labour cost for injection, number of visit 
and stress to the animals to a very ?reat extent. Therefore oil-adjuvanted 
vaccine may be preferred when compared to gel vaccine. 
4.	The maternal antibody protect the kids which were born to vaccinated 
does one to four weeks of age, regardless of the adjuvant used in the 
vaccine. 


UR  - https://krishikosh.egranth.ac.in/handle/1/5810106512
ER  -