TY - BOOK AU - Daly C Davis AU - Mammen J Abraham (Guide) TI - Hepato-renal pathology with special reference to aflatoxicosis in chicken(Gallus domesticus) U1 - 636.0896 PY - 2010/// CY - Mannuthy PB - Centre of Excellence in Pathology, College of Veterinary and Animal Sciences N2 - The present study was undertaken to study the pathology of liver and kidney in chicken under various disease conditions and to find whether aflatoxin residues were present in the liver and kidney of chicken during natural cases of aflatoxicosis. A total of 200 liver and kidney samples having lesions were collected during the period of study after detailed systematic examination of chicken brought for autopsy to the Centre of Excellence in Pathology. Aflatoxin residues in the liver and kidney were determined by Modified Pons method using Thin layer chromatography (TLC) from cases suspected for aflatoxicosis. The conditions associated with hepatic lesions were divided into bacterial diseases, viral diseases, protozoan diseases, nutrititional and metabolic diseases, aflatoxicosis , hepatic congestion and non-specific hepatosis and hepatitis. Among bacterial diseases, colibacillosis accounted for 16 percent, pasteurellosis 5.5 percent and staphylococcosis 0.5 percent. Viral disease, namely Marek’s disease accounted for 21.5 percent. Protozoan disease, histomoniasis accounted for one percent. Nutritional and metabolic diseases namely fatty liver syndrome accounted for 20.5 percent, gout (nine percent) and ascites syndrome (6.5 percent). Aflatoxicosis accounted for two percent, hepatic congestion (11 percent) and non-specific hepatosis and hepatitis (6.5 percent). The percentage incidence of various conditions associated with renal lesions included IBD 38.5 percent, Marek’s disease 21.5 percent, nephroblastoma 0.5 percent , gout nine percent, fatty liver kidney syndrome 3.5 percent, aflatoxicosis 2 percent, vascular disturbances 17 percent and non specific nephrosis and nephritis 8 percent. Aflatoxin residues from the tissues were detected only in two cases, which had aflatoxin contamination in the feed at the rate of 2 and 2.5 ppm. UR - http://krishikosh.egranth.ac.in/handle/1/5810027050 ER -