Immunopathological response of the Japanese Quail (Coturnix coturnix japonica) in experimental Aflatoxicosis (Record no. 26429)

000 -LEADER
fixed length control field 02702nam a2200181Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220826143117.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 140128s9999 xx 000 0 und d
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 636.089 6
Item number SUR/IM
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Sureshkumar M
245 ## - TITLE STATEMENT
Title Immunopathological response of the Japanese Quail (Coturnix coturnix japonica) in experimental Aflatoxicosis
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc. Mannuthy
Name of publisher, distributor, etc. Centre of Excellence in Pathology, College of Veterinary and Animal Sciences
Date of publication, distribution, etc. 1999
502 ## - DISSERTATION NOTE
Degree type MVSc
520 3# - SUMMARY, ETC.
Summary, etc. One month old Japanese quails vaccinated with Ranikhet
disease vaccine (Lasota strain) on 7th day, were divided into
three groups viz., A, B and C of 35 birds each for assessing
the immunopathological responses in experimental
aflatoxicosis. Birds of group Band C were administered
aflatoxin Bl by oral intubation at the rate of 0.5 ppm twice
weekly for two months and group .A were vaccinated with R2B
strain vaccine at the age of 46 days. Seven birds from each
group were sacrificed at fortnightly intervals for the
evaluation of various organ weights, haematological,
biochemical and haemagglutination inhibition titre values.
Liver weights and spleen weights were significantly
increased in the toxin treated birds while bursal weights were
significantly depressed from that of controls. Packed cell
volume, erythrocyte count and leucocyte counts were
significantly increased in the toxin treated birds at the end
of the experiment with a significant increase in erythrocyte
sedimentation rate at the 45th and 60th day of the experiment.
A relative heterophilia and lymphopenia were observed in the
toxin treated birds.
Serum total protein, albumin and globulin levels were
significantly depressed in the toxin treated birds but the
albumin-globulin ratio was unaltered. A relative decrease in


the haemagglutination inhibition titre values of the toxin
treated birds was recorded.
The gross and histopathological lesions in the liver of
the toxin treated birds were suggestive of progressive hepatic
degeneration, necrosis and fatty changes. There was lymphoid
depletion and vascular sclerosis in the spleen while the
bursae of the treated birds showed lymphoid depletion,
necrosis of lymphocytes, intra and interfollicular cyst
formation in increasing intensities in a time dependant
manner.
The pathomorphological alterations and a relative
depression of HI titres in the aflatoxin treated quails
indicates a moderate depression of the immune status by
aflatoxin at such a low dose level.

700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Divakaran Nair N (Guide)
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://krishikosh.egranth.ac.in/handle/1/5810101563
942 ## - ADDED ENTRY ELEMENTS (KOHA)
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          KAU Central Library, Thrissur KAU Central Library, Thrissur Theses 2014-03-18 636.089 6 SUR/IM 171477 2014-03-18 2014-03-18 Theses
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