Immunopathologic and toxic effects of endosulfan in chick embryo (Record no. 27224)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02287nam a2200181Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220305142252.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 140128s9999 xx 000 0 und d |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 636.089 6 |
| Item number | KAL/IM |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Kalai Selvan P |
| 245 ## - TITLE STATEMENT | |
| Title | Immunopathologic and toxic effects of endosulfan in chick embryo |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc. | Mannuthy |
| Name of publisher, distributor, etc. | Centre of Excellence in Pathology, College of Veterinary and Animal Sciences |
| Date of publication, distribution, etc. | 2004 |
| 502 ## - DISSERTATION NOTE | |
| Degree type | MVSc |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | The present study was undertaken to investigate the immunopathologic and toxic effects of endosulfan in chick embryo. The embryos were exposed to endosulfan at various dose levels through different routes. The weight of the embryo, bursa, thymus and spleen, histopathology of the lymphoid organs, liver, kidney and brain and quantification of the preformed maternal IgY level in the egg yolk were the parameters analysed to study the effects. Endosulfan was found to be teratogenic at the grven dose levels. The abnormalities observed were agenesis of beak, crossed beak, short lower beak, eventration of viscera and curled toe. Endosulfan did not cause any significant gross changes in the developing embryos except mild haemorrhages. Endosulfan treatment did not produce any significant reduction in the weight of the embryos as well as the weight of the lymphoid organs. On histopathological examinations endosulfan was found to be nephrotoxic and hepatotoxic to the embryos. Varying degrees of degeneration and necrosis was evident in kidney and liver. Effect on the bursa, thymus and spleen were mild to moderate where in the degenerative changes predominated. Dose dependent increase in the involution process of the thymus as evidenced by increase in the Hassal's zone was observed. The lesions in the developing lymphoid organs reflected that endosulfan is toxic to the system and going to affect the immunocompetency by way of immunosuppression and thereby rendering the chicks susceptible to various diseases. The study indicated that the endosulfan treatment did not have any effect on the preformed maternal immunoglobulin level in the egg yolk. |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Divakaran Nair N (Guide) |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | https://krishikosh.egranth.ac.in/handle/1/5810155077 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | |
| Koha item type | Theses |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Permanent Location | Current Location | Shelving location | Date acquired | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| KAU Central Library, Thrissur | KAU Central Library, Thrissur | Theses | 2014-03-18 | 636.089 6 KAL/IM | 172283 | 2014-03-18 | 2014-03-18 | Theses |