Clinical propaedeutics and rumen fluid changes in Polioencephalomalacia of Goats
By: Pame Maliekal T.
Contributor(s): Alex P C (Guide).
Material type:
BookPublisher: Mannuthy Department of Clinical Medicine, College of Veterinary and Animal Sciences 2000DDC classification: 636.089 5 Online resources: Click here to access online Dissertation note: MVSc Abstract: A study on Polioencephalomalacia was conducted in
the Department of Clinical Medicine,
College of
Veterinary and Animal Sciences, Mannuthy, for a period
of two years
(1998 and 1999). The epidemiology,
clinical findings, changes in rumen fluid, haematology
and serum biochemical changes were studied in PEM
affected goats.
Six goats affected with Polioencephalomalacia and
that responded to thiamine therapy were utilised for
this study. Detailed history was collected. Samples of
rumen fluid and whole blood from the healthy and
diseased animals were collected and analysed. Rumen
liquor
parameters,
viz. ,
physical
characters,
microbial activity, total volatile fatty acids, total
acidity, lactate and ammonia levels were recorded.
Haematological parameters like Hb, PCV, ESR, TEC, TLC
and DLC were recorded. Glucose, total protein,
albumin, lactate, pyruvate, calcium, phosphorus and
magnesium levels in the serum were estimated.
The disease occurred throughout the year with
maximum occurrence in the monsoon and post-monsoon
period. Occurrence was more in females and in the age
group of six months to five years. History suggested
carbohydrate rich diet as one of the predisposing
factor for the development of Polioencephalomalacia in
Kerala.
The clinical symptoms noted were nystagmus,
lateral deviation of head, circling and lying only on
one side.
A highly significant increase in the lactate
content of rumen fluid, was noted in goats affected
significant neutrophilia and
with
Polioencephalomalacia.
Haematology revealed
lymphopaenia indicating
stress condition. Biochemical changes in the serum
revealed significant increase in glucose, lactate and
pyruvate levels.
Th~ increase in lactate level in the rumen fluid
was not enough to induce marked lowering of the rumen
pH. Detailed cultural studies are needed to detect the
changes in rumen microbial flora in diseased goats.
Increased blood lactate and pyruvate levels indicated
thiamine insufficiency.
| Item type | Current location | Call number | Status | Date due | Barcode |
|---|---|---|---|---|---|
Theses
|
KAU Central Library, Thrissur Theses | 636.089 5 PAM/CL (Browse shelf) | Available | 171876 |
MVSc
A study on Polioencephalomalacia was conducted in
the Department of Clinical Medicine,
College of
Veterinary and Animal Sciences, Mannuthy, for a period
of two years
(1998 and 1999). The epidemiology,
clinical findings, changes in rumen fluid, haematology
and serum biochemical changes were studied in PEM
affected goats.
Six goats affected with Polioencephalomalacia and
that responded to thiamine therapy were utilised for
this study. Detailed history was collected. Samples of
rumen fluid and whole blood from the healthy and
diseased animals were collected and analysed. Rumen
liquor
parameters,
viz. ,
physical
characters,
microbial activity, total volatile fatty acids, total
acidity, lactate and ammonia levels were recorded.
Haematological parameters like Hb, PCV, ESR, TEC, TLC
and DLC were recorded. Glucose, total protein,
albumin, lactate, pyruvate, calcium, phosphorus and
magnesium levels in the serum were estimated.
The disease occurred throughout the year with
maximum occurrence in the monsoon and post-monsoon
period. Occurrence was more in females and in the age
group of six months to five years. History suggested
carbohydrate rich diet as one of the predisposing
factor for the development of Polioencephalomalacia in
Kerala.
The clinical symptoms noted were nystagmus,
lateral deviation of head, circling and lying only on
one side.
A highly significant increase in the lactate
content of rumen fluid, was noted in goats affected
significant neutrophilia and
with
Polioencephalomalacia.
Haematology revealed
lymphopaenia indicating
stress condition. Biochemical changes in the serum
revealed significant increase in glucose, lactate and
pyruvate levels.
Th~ increase in lactate level in the rumen fluid
was not enough to induce marked lowering of the rumen
pH. Detailed cultural studies are needed to detect the
changes in rumen microbial flora in diseased goats.
Increased blood lactate and pyruvate levels indicated
thiamine insufficiency.
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