Clinical investigations on parasitic anaemia in cattle

Abstract

The study “Clinical investigations on parasitic anaemia in cattle” was conducted in 50 cattle with clinical signs suggestive of anaemia. Out of the 50 animals screened 41 turned to be positive for parasites thus recording an incidence of 85 per cent for parasitic anemia. The parasitic etiology included haemoparasites, intestinal helminths and ectoparasites. Haemoparasites recorded the highest incidence rate of 78 per cent followed by intestinal helminthes (19 per cent) and ectoparasites (2.5 per cent). Anaemia due to ectoparasites was found to be least significant and was found to be pathogenic only in calves if present in large numbers. All animals were subjected to detailed clinical examination and all parameters under study viz; signalment, history, physical examination, haematology, serum biochemistry and treatment response were carried out. The data obtained were analyzed statistically. Anaemia due to intestinal helminthes was observed mostly in young calves while haemoparasites infection dominated in adult animals. Cases of anaplasmosis, and babesiosis were observed in calves below 15 days of age indicating possibility of transplacental transmission. Ectoparasites were found to cause anaemia in young calves when present in large numbers Clinical manifestations of anaemia included pallor of visible mucous membranes, exaggeration of respiration, anorexia, production depression in milch animals etc. Clinical pathology revealed reduction of packed cell volume, haemoglobin concentration and total erythrocyte count. The erythrocyte indices were within the normal range indicating normocytic normochromic anaemia. No significant changes were recorded in the mean values of thrombocyte count and total leukocyte count. Differential count revealed eosinophilic response in haemoparasite infection. Reduction in lymphocyte count was also recorded in haemoparasites infection. Serum total protein and serum albumin levels recorded a considerable decrease in the affected groups. Serum globulin and AG ratio did not show any significant changes. Serum glucose level was decreased drastically especially in group I animals. Serum bilirubin levels were significantly increased in group I animals which was due to increased erythrocyte destruction. Oxytetracyclines were used in treatment of anaplasmosis, theileriosis and ehrlichiosis. Diminazene aceturate was indicated in cases of babesiosis. Cases of strongyloides were treated by ivermectin administration. Albendazole was found effective in trichuris infection and oxyclosanide produced better clinical cure in amphistome infection. Apart from specific drugs, supportive therapy in the form of intravenous fluids, haematinics and vitamin supplements were given. Oral haematinics were found to be economical and effective. After treatment although the haematological values came to normal levels, significant decrease from control group was observed in packed cell volume, haemoglobin concentration and total erythrocyte count. This was attributed to the lag period occurring for the normalization of these parameters. Thus treatment was found to be effective with good clinical response and haematobiochemical parameters returning to normal levels. But few deaths were recorded. This could be due to the severity of infection which was evident from the drastic reduction in the haematological parameters